What is Nonalcoholic steatohepatitis (NASH)?
Nonalcoholic Steatohepatitis (NASH) is an advanced form of Nonalcoholic Fatty Liver Disease (NAFLD) characterized by liver inflammation and damage in addition to fat buildup. Unlike simple fatty liver (steatosis), NASH involves inflammation and scarring (fibrosis), which can progress to cirrhosis or liver cancer over time.
NASH typically occurs in individuals who drink little or no alcohol but have metabolic risk factors such as obesity, insulin resistance, high cholesterol, or type 2 diabetes. Because NASH often develops silently, many people are unaware they have it until significant liver damage has occurred.
Is Nonalcoholic steatohepatitis common?
NASH affects about 3–5% of adults worldwide and is more common in people with obesity or diabetes. It is currently one of the leading causes of liver transplantation in the United States and is expected to become the most common cause in the coming years.
Can Nonalcoholic steatohepatitis be cured?
There is no specific cure for NASH yet, but its progression can often be slowed or even reversed with early intervention. Lifestyle changes, weight loss, and medical management of associated conditions like diabetes and high cholesterol can significantly improve liver health.