Insect Hypersensitivity

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What is Insect Hypersensitivity?

Insect hypersensitivity is an allergic reaction that occurs when the body’s immune system overreacts to proteins found in the saliva, venom, or body parts of insects such as bees, wasps, hornets, ants, mosquitoes, or other stinging or biting insects. Reactions can range from mild localized swelling to severe, life-threatening systemic responses such as anaphylaxis.

This condition is part of a spectrum of allergic disorders and may develop in people with other allergies, such as asthma, eczema, or food allergies. While most insect bites or stings cause minor irritation, hypersensitive individuals experience exaggerated immune responses.

Is Insect Hypersensitivity common?

Mild reactions to insect bites are common, but true insect hypersensitivity is less frequent. Reactions to stings, particularly from bees or wasps, are more likely to cause severe allergic responses. People who experience severe reactions to insect stings are at higher risk of recurrence and require careful management.

Can Insect Hypersensitivity be cured?

There is no permanent cure for insect hypersensitivity, but reactions can be effectively managed. Avoiding stings, carrying emergency medications, and undergoing venom immunotherapy in selected cases can prevent severe reactions and improve quality of life.

Causes

What causes Insect Hypersensitivity?

Insect hypersensitivity occurs when the immune system reacts abnormally to proteins in insect venom or saliva. Common causes include:

  • Stings from bees, wasps, hornets, or ants – venom triggers immune response
  • Bites from mosquitoes, fleas, or other insects – saliva proteins can cause allergic reactions
  • Genetic predisposition – family history of allergies increases risk
  • Other atopic conditions – asthma, eczema, or food allergies can raise susceptibility

What are the risk factors?

You may be more likely to develop insect hypersensitivity if you:

  • Have a personal or family history of allergies
  • Have other allergic conditions such as asthma, eczema, or food allergy
  • Have experienced prior severe reactions to insect stings
  • Are frequently exposed to insects due to work, hobbies, or living conditions

With Insurance

Without Insurance

*Price Effective 12/1/2025
$169
Initial Visit
$109
Follow Up

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Symptoms

What are the symptoms of Insect Hypersensitivity?

Symptoms can range from mild to severe and include:

Mild to moderate reactions:

  • Redness, swelling, or itching at the bite or sting site
  • Localized pain or warmth
  • Hives or rash near the site

Severe systemic reactions:

  • Swelling of lips, tongue, throat, or face (angioedema)
  • Difficulty breathing or wheezing
  • Rapid heartbeat or dizziness
  • Nausea, vomiting, or abdominal pain
  • Low blood pressure and fainting

Anaphylaxis:
A severe, life-threatening allergic reaction that requires immediate medical attention. Symptoms include throat swelling, difficulty breathing, widespread hives, dizziness, and potential loss of consciousness. Some individuals develop large local reactions, where swelling extends beyond the sting area but remains limited to one region of the body.

Diagnosis

How is Insect Hypersensitivity diagnosed?

Diagnosis typically involves:

  • Medical history – evaluating previous reactions, timing, and suspected insects
  • Physical examination – to assess skin reactions and systemic symptoms
  • Skin prick tests – using small amounts of insect venom to detect allergic response
  • Blood tests – measuring specific IgE antibodies to insect venom
  • Observation of reaction patterns – assessing the severity and frequency of reactions

Accurate diagnosis helps guide treatment, preventive measures, and the need for emergency preparedness.

Treatment

How is Insect Hypersensitivity treated?

Treatment depends on severity and includes prevention, medication, and emergency management:

Prevention and lifestyle measures:

  • Avoiding insect exposure when possible
  • Wearing protective clothing outdoors
  • Using insect repellents and safe living environment practices

Medications:

  • Antihistamines – to relieve mild itching, swelling, or hives
  • Corticosteroids – to reduce inflammation in severe reactions
  • Epinephrine (adrenaline) – for severe systemic reactions or anaphylaxis
  • Bronchodilators – for breathing difficulties during reactions

Immunotherapy:

  • Venom immunotherapy (VIT) – a long-term treatment that gradually desensitizes the immune system to insect venom, reducing the risk of severe reactions

Emergency preparedness:

  • Carry an epinephrine auto-injector if prescribed
  • Have an action plan for accidental stings or bites
  • Inform friends, family, and colleagues about your allergy

With proper avoidance, treatment, and emergency planning, most individuals with insect hypersensitivity can lead safe and active lives while minimizing the risk of severe allergic reactions.

References

  • Mayo Foundation for Medical Education and Research. (2024, April 5). Insect Sting Allergy. Mayo Clinic. https://www.mayoclinic.org
  • U.S. National Library of Medicine. (2024, March 1). Insect Allergy. MedlinePlus. https://medlineplus.gov
  • American Academy of Allergy, Asthma & Immunology. (2023). Insect Allergy. https://aaaai.org
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Affordable – with or without insurance

With Insurance

Without Insurance

*Price Effective 12/1/2025
$169
Initial Visit
$109
Follow Up

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